Tag: wound care

Adcock Ingram Critical Care Partners with Convatec to Supply Advanced Medical Products

Convatec’s Esteem stoma care system

Adcock Ingram Critical Care (AICC), a leading manufacturer and supplier of hospital and critical care products in Southern Africa, is expanding its reach in Ostomy and Advanced Wound Care. On 1 February 2024, AICC and Convatec signed a sales, marketing and distribution agreement covering South Africa and neighbouring countries.

Convatec is a globally renowned medical products and technologies company focused on therapies for managing chronic conditions, with leading positions in advanced wound care, ostomy care, continence care, and infusion care.

Colin Sheen, MD at AICC says: “This strategic agreement will add an important new pillar to AICC’s business. As a key pharmaceutical company in Southern Africa, AICC takes its responsibility towards healthcare professionals and patients seriously. As part of our commitment and responsibility to healthcare providers and patients, this agreement between AICC and Convatec is aligned with our mission to provide quality products that improve the health and lives of people in the markets we serve.”

The agreement extends throughout South Africa and neighbouring countries, and includes the import and distribution of a range of finished products in Advanced Wound Care, Ostomy Care and Continence Care. Convatec’s solutions provide various clinical and economic benefits that include infection prevention, protection of at-risk skin, and improved patient outcomes.

Sameer Singla, Vice President – Asia, Middle-East, Africa (AMEA) at Convatec says: “Convatec is pleased to partner with AICC to extend the reach of our products and solutions for patients. Convatec is committed to supporting people living with challenging medical conditions, and to addressing the care gap between the support patients need and what healthcare professionals can provide, which underpins our ‘forever caring’ promise. We look forward to partnering with AICC to meet the needs of patients and healthcare professionals.”

Astronauts Will Test A Portable Bioprinter for Wounds

ESA astronaut Matthias Maurer is shown during preflight training for the BioPrint First Aid investigation, which tests a bioprinted tissue patch for enhanced wound healing.
Credit: ESA

A suitably advanced piece of wound care technology will be sent into orbit to the space station in the next few days: a prototype for portable bioprinter that can cover a wound area on the skin by applying a tissue-forming bio-ink that acts like a patch, and accelerates the healing process.

While the aim is to provide a effective wound treatment for astronauts millions of kilometres from the nearest hospital, such a personalised wound healing patch would also have a great benefit on Earth. Since the cultured cells are taken from the patient, immune system rejection is unlikely, allowing a safe regenerative and personalised therapy. Other advantages are the possibilities of treatment and greater flexibility regarding wound size and position. In addition, due to its small size and portability, physicians could take the device anywhere to an immobile patient if their cells were cultivated in advance.

“On human space exploration missions, skin injuries need to be treated quickly and effectively,” said project manager Michael Becker from the German Space Agency. “Mobile bioprinting could significantly accelerate the healing process. The personalised and individual bioprinting-based wound treatment could have a great benefit and is an important step for further personalised medicine in space and on Earth.”

The use of bioprinting for skin reconstruction following burns is one growing application for the technology. However, it presently requires large bioprinters that first print the tissue, allow it to mature, before it is implanted onto the patient. By testing it in the gravity-free environment of space, Bioprint FirstAid will help optimise of bioprinting materials and processes. Microgravity-based 3D tissue models are important for greater understanding of the bioengineering and bio-fabrication requirements that are essential to achieve highly viable and functional tissues. Under microgravity conditions, the pressure of different layers containing cells is absent, as well as the potential sedimentation effect of living cell simulants. The stability of the 3D printed tissue patch, and the potentially gravity-dependent (electrolyte to membrane interface) crosslinking process, can be analysed for future applications.

The Bioprint FirstAid prototype contains no cells at this point. The surprisingly simple prototype is a robust, purely mechanical handheld bioprinter consisting of a dosing device in the handle, a print head, support wheels, and an ink cartridge. The cartridge contains a substitution (in total two different substitutions, both without skin cells) and a crosslinker, which serves as a stabilising matrix. To test it out, the simulant will be applied to the arm or leg of a crew member wrapped in foil, or alternatively at any other surface wrapped in foil. On Earth, a printed sample with human cells will be tested, and the distribution pattern will be compared to the cell-free sample that was printed in space.

Source: NASA

Improved Wound Healing with Platelet-rich Plasma

Image by Dian Polekhina on Unsplash

New research suggests that wound healing could be enhanced by replicating platelet-rich plasma from our blood to create implants introduced into the wound.

Platelet-rich plasma (PRP) is a natural healing substance in our blood. Researchers explored ways of enhancing the wound healing process by extracting PRP from the blood of a patient with a complex skin wound and manipulating it through 3D printing to form an implant for tissue repair which can be used to treat difficult-to-heal skin wounds in a single surgical procedure.

The results, which are reported in Advanced Functional Materials, showed that application of the 3D-printed PRP implant helped to speed up the healing of the wound by enabling efficient vascularisation and inhibiting fibrosis, which are both essential for effective wound healing.

Professor Fergal O’Brien, at RCSI University of Medicine and Health Sciences said: “Existing literature suggests that while the PRP already present in our blood helps to heal wounds, scarring can still occur. By 3D-printing PRP into a biomaterial scaffold, we can increase the formation of blood vessels while also avoiding the formation of scars, leading to more successful wound healing.

“As well as promising results for skin wound healing, this technology can potentially be used to regenerate different tissues, therefore dramatically influencing the ever-growing regenerative medicine, 3D printing and personalised medicine markets.”

Source: RCSI

New “Spray-on” Wound Dressing Mimics Skin

A new kind of burn dressing developed by an Israeli company, Nanomedic, is being used in Israel, Europe and India, and applies a flexible dressing without contact.

Called “Spincare”, it is contactless and is sprayed on by an applicator. Normal burn dressings are difficult to apply because they can cause so much pain.The breathable “skin substitute” is flexible, which is important for allowing movement for wound rehabilitation, and is also easy for patients to apply. Unlike traditional wound dressings, it also allows patients to shower, and, being translucent, allows clinicians to inspect the wound without having to remove the dressing.

The technology is based on “electrospinning“, where electricity is applied to a solution to make nanofibres. Electrospinning had mostly been used to produce air filters, but it was only until the 1990s that the technology began to acquire other applications. Though the technology has been used in medical applications before, this is the first time such a device small enough to use at a patient’s bedside has been developed.

It is effective at treating shallow burns, but less effective for deep burns, according to the manufacturer. It also has applications in areas such as facial wound dressings, where traditional bandages are cumbersome, This new technology comes at a time when there is debate in wound care management, as to whether frequent replacement of dressing for checking purposes is in fact counterproductive. This new technology would join other types of wound dressing increasingly being used that require fewer changes.

Source: The Guardian