Tag: healthcare politics

Categories : COVIDTags :

Biden’s Promise to “Manage the Hell” out of COVID

On By ModernMedia

Almost immediately upon assuming office, the newly sworn-in President Joe Biden started to deliver on his promise to tackle the COVID pandemic raging in the United States.

On Wednesday, shortly after being sworn in, he wrote to both the United Nations Secretary General and the WHO Director General to notify them of the United States’ return to the WHO – a move no doubt welcomed around the world. He also began to sign a raft of orders related to the COVID pandemic.

Following up on his promise to “manage the hell” out of the COVID pandemic, President Biden signed a directive which “seeks to support the international health and humanitarian response to the COVID-19 pandemic and its secondary impacts, global health security and diplomacy, and better biopreparedness and resilience for emerging and future biological threats.”

His actions and executive orders include:– Increased equipment procurement. Using the Defense Production Act (DPA) to accelerate manufacturing and meet shortfalls in COVID-related equipment and supplies.
– Increased COVID testing. Another order establishes a testing board to help expand the supply of tests and testing equipment, as well as supporting the public healthcare force.
– Increasing studies on COVID-19 treatments. More studies requested on COVID, as well as on COVID in diverse populations. Also requests more healthcare workers.
– Speeding up vaccinations. Federal Emergency Management Agency (FEMA) is directed to begin deploying vaccination centres, aiming toward a goal of 100 in the next month.
– Reopening schools and businesses. The Departments of Education and Health and Human Services (HHS) are directed to provide guidance on safe reopening and operating for education institutions and child care providers.
– Improving protections for workers. Clear guidance for employers to keep employees safe from COVID exposure.
– Increasing travel safety. Masks are to be worn in federal buildings, and mask requirements are extended to interstate travel, including on planes, trains, and buses. People flying into the US from another country will need to test negative for COVID prior to departure and quarantine upon arrival.

President Biden’s plan and the full texts of the executive orders were detailed in a 200 page document which was made available on Thursday.

At a White House signing ceremony, he affirmed his commitment to “following the science” on COVID, saying: “We will make sure that scientists and public health experts will speak directly to you — not the president, but real, genuine experts and scientists.” He added that they will work free of political interference.

He also warned Americans of a “dark winter” ahead, and the nation was in a national emergency and that “we should treat it like one.”

Source: MedPage Today

Categories : COVIDTags :

WHO Warns of ‘Catastrophic Failure’ over COVID Vaccination

On By ModernMedia

The World Health Organization head, Dr Tedros Adhanom Ghebreyesus, has warned that the world faces a “catastrophic moral failure” because of unequal access to COVID vaccines. 

He said that 49 wealthier states had conducted 39 million vaccinations between them, but one poor country had only 25 doses.

To date, the US, China, India, Russia and the UK have all developed vaccines, and mostly prioritised their own populations to receive them – although the German company BioNTech developed theirs in collaboration with Pfizer, and even so, the EU failed to secure vaccines sufficiently in advance. 

Dr Tedros spoke to an executive board session of the WHO, saying: “I need to be blunt: the world is on the brink of a catastrophic moral failure – and the price of this failure will be paid with lives and livelihoods in the world’s poorest countries.”

He warned that a selfish approach to vaccination would lead to hoarding and rising prices.

“Ultimately, these actions will only prolong the pandemic, the restrictions needed to contain it, and human and economic suffering,” he added.

Calling on nations to accelerate their progress, he said: “My challenge to all member states is to ensure that by the time World Health Day arrives on 7 April, Covid-19 vaccines are being administered in every country, as a symbol of hope for overcoming both the pandemic and the inequalities that lie at the root of so many global health challenges.” 

Thus far, 180 countries have signed on to the Covax initiative, which aims to negotiate as a bloc for lower vaccine prices. The initiative aims to distribute vaccines to low- and middle income countries, 92 of which will have their vaccines paid for by the initiative. Dr Tedros said that two billion doses had been secured, with an option of a billion more, with the first doses delivered by February.

UK Health Secretary Matt Hancock said in a reaction to Dr Tedros’ warnings that, “The UK is the world’s biggest supporter, financial supporter, of the global programme to ensure access to vaccines in all countries in the world.”

The UK has contributed £548m ($734m) to the Covax initiative. Canada drew criticism after it was revealed that, due to vaccine hoarding, the 70 poorest countries would only be able to vaccinate 10% of their population, while Canada had secured enough vaccines for five times its population of nearly 38 million. However, these vaccines are “hypothetical” according to Karina Gould, Canada’s minister of international development. Canada is also contributing $380 million to Covax. Furthermore, discussions are reportedly under way for South Africa to secure some of the vaccines allocated to Canada.

Source: BBC News

Categories : COVID UncategorizedTags :

SA Government Aims for a Corruption-free Vaccine Programme

On By ModernMedia

In the past week, President Cyril Ramaphosa and health minister Zweli Mkhize have undertaken a publicity drive to demonstrate how the government is working to ensure a tightly controlled vaccine drive that is not plagued by corruption. This is to avoid a repeat of the corruption in PPE acquisition last year, with some R10.5 billion being investigated for looting, with an Auditor-General report finding some items being purchased at five times the going price.

These efforts include centralised transactions which involve the auditor-general looking out for any discrepancies. Vaccine acquisition and roll-out planning will be handled by the government, with the private sector being tapped for storage and distribution. “What we have done is to get the Treasury and the Department of Health’s office of the chief procurement officer to oversee any form of transaction that is going to happen.

“Right now the procurement of the vaccines is within government. It makes it easier because it’s a tight-knit set of people, the prices are known, the manufacturers are known, the deviation is specific and it’s not the same as what we had in PPE where there were so many vendors, suppliers and so many different prices,” he said.

Furthermore, there will be consultation with the Attorney General. “We are going to say [to the AG]… these are the risks we have identified and ask them to analyse our plans and see if there are further risks we must be aware of and how we can work together to prevent any risk of looting,” Mkhize said.

Medical aid schemes have voiced concerns over the process, having sourced vaccines for their members as well as contributing to the vaccination costs of those not covered by any medical aid scheme.

President Ramaphosa said that South Africa would have pre-paid like other countries to secure vaccines, even given the risks of them failing, if it had the funds to do so.

However, he affirmed that there are funds available to buy the vaccination scheme, saying: “we are going to have the money, it will come from Treasury. There is just no way we can say, when it comes to saving the lives of South Africans, that we don’t have the money. The money will be there. It has to be there to save the lives of South Africans. That one will be my bottom line.”

The Covax programme will provide a vaccine for 10% of the population in the second quarter of 2021, for which a deposit of R283 million has been paid. A further 1.5-million vaccine doses have been secured from AstraZeneca and 9-million from Johnson & Johnson (J&J). The J&J vaccine only requires a single dose to confer immunity, so should be able to cover 9 million people.

“J&J will be producing through Aspen here at home, and we are hoping to get the bulk of our supply from there, once the production starts,” said Ramaphosa.

Source: Times Live

Categories : COVIDTags :

EU Angered by Pfizer Delay

On By ModernMedia

Pfizer has said in a statement on Friday that the drop in production is the result of the company upgrading its manufacturing processes, and that there will be an overall increase in supply as a result.

“Although this will temporarily impact shipments in late January to early February, it will provide a significant increase in doses available for patients in late February and March,” Pfizer said.

The German health ministry has said the delays are surprising and regrettable, pointing out that it had secured binding mid-February delivery dates from the company. EU Commission President Ursula von der Leyen said that she had been given assurances by Pfizer’s chief executive that all orders for the first quarter would arrive. She had previously said that Pfizer had promised to double its delivery of doses to the EU to 600 million this year.

However, the EU also has agreements in place with Moderna to supply vaccines, and this is not wholly dependent on Pfizer. However, Johnson & Johnson is also falling behind in its vaccine delivery targets, amidst reports that the US has failed to meet vaccination goals for the end of 2020, and may struggle to meet this year’s goals. Meanwhile, the UK is expected to be slightly impacted by the drop in supply but remains on track to meets its February immunisation goals.

However, the EU has lagged behind the UK in its vaccination programme, for a number of reasons including the fact that the UK ordered and approved its vaccines sooner, while Brussels’ negotiations were slower. Much of the delay is due to the added bureaucracy of the 27 nation political confederation and its decision to acquire vaccines as a single entity instead of individual countries further exacerbated this.

According to Reuters, citing a participant at a meeting last week, a third of the EU’s 27 countries reported difficulties in securing enough vaccines for their vaccination programmes.

Source: BBC News

Categories : UncategorizedTags :

Controversy Reigns over Remdesivir FDA Approval

On By ModernMedia

According to an article by Science, the approval of remdesivir by the US Food and Drug Administration (FDA) has shown irregularities in the approval process.

Remdesivir is particularly well-remembered for being approved by the FDA for emergency use, and again for the results of the Solidarity trial, which was organised by the WHO across the world. The Solidarity trial had shown no benefit for mortality benefit for remdesivir – or any other measures. There were high hopes for remdesivir initially: early on, an NIH trial found that it shortened the disease – but a similar Chinese study found no evidence of that. A later study sponsored by remdesivir’s manufacturer, Gilead, found that it reduced recovery time for a 5 day course – but not for a 10 day course. Gilead was aware of the Soldiarity results early on, and then when they became public because they were conducted across multiple countries with different standards of care.

Meanwhile, the FDA went ahead with its approval process. The Solidarity researchers described the results to the FDA on Oct. 10, and in a preprint paper five days later, but the FDA still gave approval, apparently ignoring the Solidarity results in favour of those of the NIH and other studies. Furthermore, the FDA had not convened a key advisory group – yet it had for all of the COVID vaccine approvals.

Meanwhile, the European Commission signed a procurement for 500 000 doses of remdesivir worth $1.2billion. A European Commission spokesperson confirmed that it only received word of the failure of remdesivir in the Solidarity trial the following day.

Categories : UncategorizedTags :

Biden to Hit the Ground Running with COVID Response

On By ModernMedia

Mounting an effective response to COVID was one of presidential hopeful Joe Biden’s campaign promises, and now that he has won the US elections, he is seeking to implement this response as soon as possible.

This comes at a critical time, as the US has been struggling with record new cases, breaking 100 000 per day in the last few days, with sombre predictions of another 100 000 deaths by January, stoked by the advent of winter and people socialising for the festive season. Biden has begun assembling a science-focussed team to prepare to take on managing the COVID pandemic as soon as he takes office.

Numerous challenges will face Biden’s team when he assumes office. One of them is the extreme distrust that has emerged as a result of the politicisation of the virus. 

Angela Rasmussen, a virus researcher at Columbia University in New York, said: “The past year of misinformation, confusion and gaslighting from the White House has really left people without any trust that our government is capable of handling this. It’s going to be critical to begin communicating that, yes, this administration will be led by the science.” 

 Some believe that, unfortunately, that it is a case off too little, too late, and that attitudes cannot be so easily changed. Kris Mathews, the administrator of Decatur Health, a small hospital in rural Kansas, said, “I think the damage is done. People have made up their minds about how they react to it.”  

Biden has also promised to have the US rejoin the World Health Organization on the first day of his presidency. Dr. Soumya Swaminathan, the WHO’s chief scientist, said: “Everyone recognises that for a pandemic, you cannot have a country-by-country approach. You need a global approach.” She expressed optimism that the US under Biden would join the global Covax scheme led by the WHO to distribute the vaccine to the needy.

Source: Medical Xpress

Categories : COVIDTags :

No Lockdown May Worsen Economies

On By ModernMedia

In an article for The Conversation, Michael Smithson of the Australian National University argues that far from there being a toss-up between saving lives with a lockdown, and protecting the economy by keeping a country open, lockdown may in fact protect the economy.

Some arguments even leaned towards Indeed, US Treasury Secretary Steve Mnuchin said in June, “I think we’ve learned that if you shut down the economy, you’re going to create more damage.”

The choice of whether to implement lockdown has been a particularly difficult choice to make for South Africa, beset by deep inequality. Its lockdown caused its economy to shrink by 51% in the second quarter.

Economic and COVID data from 45 countries was sourced for analysis. The data has two outliers; namely China, which implemented a very effective early lockdown, and India, which implemented a strict lockdown that became very ineffective as time went by.

Consumer expenditure, an important indicator of economic activity, was negatively correlated with COVID cases, indicating that the economy fared better with attempts to suppress the virus (at least temporarily).

In European countries, GDP was positively correlated with COVID cases, indicating that economic activity itself drove up the rate of COVID cases. 

The article’s conclusions do have some limitations. The economic data were drawn from the second quarter, and COVID cases were taken as of June 30, but the pandemic hit different countries at different times. 

Categories : COVIDTags :

Effectiveness of COVID Government Interventions Compared

On By ModernMedia

Currently, the most widely used tool to deal with the spread of COVID are non-pharmaceutical interventions (NPIs), which involve measures such as social distancing. In the face of the sudden emergency of the COVID pandemic, governments around the world implemented a wide range of NPIs, some based on scientific advice and some not. The effectiveness of these government interventions is compared in a new study.

In order to evaluate the effectiveness of these responses, researchers studied government interventions across 79 countries and territories. Each item was ranked, making a comprehensive dataset of 6068 interventions and compared to the reproduction number, Rt. They were analysed with four computational methods, including machine learning.

The study found that the most effective interventions were those that restricted movement such as travel restrictions and lockdowns, as well as social distancing. Cancellations of gathering also seemed to be effective. The least effective were appeals for international aid, tracking and tracing, disinfecting surfaces had the least impact.

Interventions also had differing effectiveness depending on what stage of the pandemic they were implemented in.

The most consistently effective intervention across all locations was contact tracing and quarantine.

Source: News-Medical.Net

Categories : COVIDTags :

COVID and Vaping Lung Injuries can be Confused

On By ModernMedia

Three recent case studies show that breathing problems in teens could be a result of vaping or COVID, according to a UC Davis Health paediatric team.

Known as e-cigarette, or vaping, product use-associated lung injury (EVALI), it is present in large numbers. As of February 2020, 2758 cases of EVALI were hospitalised, with 64 deaths in the United States, and over half of those hospitalised were under 25 years old.

“EVALI and COVID-19 share many symptoms but have very different treatment plans,” said lead author Kiran Nandalike, associate professor of paediatrics. “For this reason, providers caring for pediatric patients with unexplained respiratory failure should consider EVALI and ask for relevant smoking/vaping history.”

EVALI and COVID patients often present with fever, cough, nausea, abdominal pain and diarrhoea. Bilateral ground glass opacities are seen in chest imaging in both conditions.

Adolescents often use vaping with marijuana obtained through friends, family and unlicenced dealers, with products often containing vitamin E acetate, an additive which is strongly associated with lung injury. Isolation and stress as a result of the COVID pandemic increased usage.

In the case studies, all of the patients had fever, nausea and cough, as well as a high heart rate, rapid breathing and low blood oxygen levels. Laboratory results showed higher white blood cells (WBC) count and elevated inflammation, pointing to COVID inflammation. Chest imaging revealed nonspecific ground glass opacities. Despite all other findings indicating COVID, SARS-CoV-2 testing was negative. The patients were successfully treated with steroids, a potentially life-saving treatment for EVALI.

“To help reduce risk of EVALI recurrence, providers would recommend vaping cessation counseling to patients and close outpatient monitoring,” advised Nandalike.

Source: Medical Xpress