Tag: 12/9/22

Categories : Cardiovascular Disease VaccinesTags :

Flu Vaccine May Reduce Ischaemic Stroke Risk

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Receiving an annual flu vaccination may be linked to a reduction in risk of ischaemic stroke, according to a study which appears online in the journal Neurology.

“Studies have shown that getting the flu increases your risk of having a stroke, but research is still being collected on whether getting the flu vaccine can help protect against a stroke,” said study author Francisco J. de Abajo, MD, MPH, PhD, of the University of Alcalá in Madrid. “This observational study suggests that those who have a flu shot have a lower risk of stroke. To determine whether this is due to a protective effect of the vaccine itself or to other factors, more research is needed.”

In their study, the researchers accessed a health care database in Spain, identifying 14 322 participants aged 40 years and over with a first stroke over a 14-year period. Each person who had a stroke was matched to five people of the same age and sex who did not have a stroke.

Then the researchers looked at whether people had received the influenza vaccine at least 14 days before the stroke or before that same date for those who did not have a stroke.

A total of 41.4% of those who had a stroke had received the flu vaccine, compared to 40.5% of those who did not have a stroke – seemingly indicating that the flu jab added to risk. But those vaccinated were more likely to be older and to have other stroke risk factors such as hypertension and high cholesterol. Once these were adjusted for, the researchers found that those who received a flu shot had a 12% reduced stroke risk.

The pneumonia vaccine was also investigated for any effect on the risk of stroke, but none was found.

“These results are yet another reason for people to get their yearly flu shot, especially if they are at an increased risk of stroke,” de Abajo said. “To be able to reduce your risk of stroke by taking such a simple action is very compelling.”

Since the study was observational, it only shows an association and cannot prove a causal link. Other unmeasured factors could also mediate stroke risk,

Source: American Academy of Neurology

Categories : Metabolic Disorders Obstetrics & GynaecologyTags :

Obesity and Diabetes in Pregnancy may Raise Child’s ADHD Risk

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Boy hanging from tree
Photo by Annie Spratt on Pexels

A recent study has found that children born to women with gestational diabetes and obesity may have twice the risk of developing attention-deficit/hyperactivity disorder (ADHD) compared to those born to mothers without obesity. The findings, published in the Journal of Clinical Endocrinology & Metabolism, also found found that in women with a healthy weight gain during pregnancy, this risk increase was not seen.

ADHD is a growing problem. According to data from 2016-2019, 6 million children aged 3–17 years have received an ADHD. Maternal obesity is a major risk factor for ADHD in children, and roughly 30% of women have obesity at their first doctor’s visit during pregnancy, rising to 47% in women with gestational diabetes. Excessive weight gain during pregnancy in this population is a risk factor for children developing ADHD.

“Our study found pregnant women with obesity and gestational diabetes had children with long-term mental health disorders such as ADHD,” said Verónica Perea, MD, PhD, of the Hospital Universitari Mutua Terrassa in Barcelona. “We did not find this association when these women gained a healthy amount of weight during pregnancy.”

Studying 1036 children born to women with gestational diabetes, the researchers found that 13% of these children were diagnosed with ADHD. When compared to mothers without obesity, the researchers found children of women with gestational diabetes and obesity were twice as likely to have ADHD compared to those born to mothers without obesity.

Notably, this association was only seen in women with gestational diabetes, obesity and excessive weight gain during pregnancy. There was no increased risk of ADHD in children of women with gestational diabetes and obesity if the amount of weight these women gained during pregnancy was within the normal range.

“It’s important for clinicians to counsel their patients on the importance of healthy weight gain during pregnancy,” Perea said.

Source: The Endocrine Society

Categories : Skeletal SystemTags :

Weight Loss Protects against Structural Defects of Knee Osteoarthritis

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Researchers conducting long-term follow ups of adults given knee X-rays found that a decrease in body mass index (BMI) was associated with both a lower incidence of the structural defects of knee osteoarthritis. Published in Arthritis & Rheumatology, also found reduced odds of these defects progressing.

In the study radiographic analyses were conducted of adults’ knees with and without the structural defects of knee osteoarthritis at baseline and at 4 to 5 years’ follow up from adults. A total of 9683 knees (from 5774 individuals) were assessed in an ‘incidence cohort’ along with 6075 knees (from 3988 individuals) in a ‘progression cohort.’

The researchers observed that a 1-unit drop in BMI was linked to a 4.76% reduction in odds of the incidence and progression of knee osteoarthritis. A 5-unit BMI drop, which can downgrade a BMI category (eg, from overweight to normal), reduced the odds of incidence and progression by 21.65%.

“These findings could be empowering for people with or at risk of knee osteoarthritis,” said lead author Zubeyir Salis, BEng, and a PhD student for Public Health at the University of New South Wales in Australia. “The current prevailing view is that knee osteoarthritis is part of ageing and that we have no control over it. However, my analyses suggest that some people could potentially prevent, slow or delay knee osteoarthritis by losing weight.”

Source: Wiley

Categories : Environmental EffectsTags :

Extreme Temperatures will Affect Sleep as Climate Change Progresses

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With heatwaves becoming increasingly common around the world, researchers examined how outdoor nighttime temperature changes affect body temperature and sleep quality. Their literature review published in the Journal of Sleep Research, the researchers suggest that high, uncomfortable temperatures can disrupt sleep by interfering with the body’s normal thermoregulation ability.

A recent study found that on average in Europe, the number of days with extreme heat (ie >99% percenticle) has tripled since 1950. Even temperatures on extremely hot days have increased by 2.3 °C throughout the same period. In the future, these heatwaves will be more frequent and of longer duration. Of particular concern is that nighttime temperatures will increase more than daytime ones – and high nighttime temperatures are associated with increased mortality risk.

The authors, from the European Insomnia Network, note that there are certain groups such as older adults, children, pregnant women, and individuals with psychiatric conditions, who may be especially vulnerable to the sleep disruptive effects of heatwaves. They also offer several coping methods adapted from elements of cognitive behavioural therapy for insomnia. 

“This paper is considered to be important and timely to disseminate expert recommendations to the research and clinical community as well as to the general population,” the authors wrote. “Nevertheless, it points out several areas of research which are still lacking, especially for specific populations. Even more important, literature evidence is still scarce.”

Source: Wiley

Categories : Environmental EffectsTags :

Not Just Reactive: Dermatology’s Role to Fight Climate Change

On By ModernMedia

In addition to the skin-related impacts of climate change, the field of dermatology also has to address its own contribution to global warming. A commentary in the International Journal of Dermatology stresses the need for dermatologists to engage more meaningfully on key climate issues and to move beyond discussions of the skin-related impacts of climate change.

The article follows a 2021 editorial published en masse by 233 international medical journals that called for emergency action to limit global warming and adverse health effects related to climate change.

The authors of this new commentary note that they and other dermatologists are professionally charged with diagnosing, treating, researching, and mitigating the health harms from climate change but also must consider that healthcare is among the most carbon-intensive service sectors worldwide.

They point out that significant reductions in carbon emissions are readily achieved in dermatology by increased use of telehealth services and virtual medical meetings and residency interviews. Also, dermatologists should prioritise funding for climate-health research to improve healthcare sustainability and decarbonise the profession.

“Our research, advocacy, and policies must be ambitious in scope, reaching beyond cutaneous disease to integrate the impact of climate change on social determinants of health and support resiliency and social justice invulnerable populations,” the authors wrote. “We have an ethical imperative to act. The time is now for dermatologists and our medical societies to collectively rise to meet this crisis.”

Source: Wiley

Categories : UncategorizedTags :

Can Good Dental Health Protect against Dementia?

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Dentist checking teeth
Image by Caroline LM on Unsplash

A major analysis of all relevant published studies indicates that poor periodontal health and tooth loss may increase the risk of both cognitive decline and dementia. The finding, published in the Journal of the American Geriatrics Society, affirms a long-suspected connection between dental and cognitive health.

The analysis included 47 studies. Poor periodontal health, reflected by having periodontitis, tooth loss, deep periodontal pockets, or alveolar bone loss, was linked to a 23% increase in risk for cognitive decline and a 21% higher risk of dementia. Tooth loss on its own was associated with a 23% higher odds of cognitive decline and a 13% higher risk of dementia. The overall quality of evidence was low, however.

“From a clinical perspective, our findings emphasise the importance of monitoring and management of periodontal health in the context of dementia prevention, although available evidence is not yet sufficient to point out clear ways for early identification of at-risk individuals, and the most efficient measures to prevent cognitive deterioration,” the authors wrote.

Source: Wiley