Day: January 3, 2023

Celebrations can Benefit Well-being and Health

Photo by Myriam Zilles on Unsplash

Making an intentional effort to mark positive life events and achievements while gathering for food and drink will leave people feeling more socially supported, according to new research published in the Journal of Public Policy & Marketing.

The researchers found that celebrations with three conditions – social gathering, eating or drinking, and intentionally marking a positive life event – will increase perceived social support. Perceived social support, according to prior studies, is the belief that having a social network will provide support in case of future, negative life events. That belief is associated with health and well-being outcomes, including increased life-span and decreased anxiety and depression.

“Many celebrations this time of year include two of the three conditions — eating and drinking while gathering together,” said study co-author Kelley Gullo Wight, assistant professor at the Indiana University Kelley School of Business. “Adding the third condition, making an intentional effort to recognise other’s positive achievements, is key. For example, take the time to congratulate someone for getting accepted to their first-choice university, or a work project that went well, or a new job offer. This will maximise the benefits to your well-being and the well-being of all the attendees at that holiday party.”

Wight and her co-authors used behavioural experiments to survey thousands of participants over several years.

The findings showed that even if gatherings are virtual, if everyone has food and drink (no matter if it’s healthy or indulgent) and they’re celebrating positive events, this also increases a person’s perceived social support, and they can receive the same well-being benefits from it.

It also has implications for marketing managers or anyone looking to raise funds for a good cause.

“We found that when people feel supported socially after a celebration, they’re more ‘pro-social,’ and more willing to volunteer their time or donate to a cause,” said co-author Danielle Brick, assistant professor of marketing at the University of Connecticut. “This would be a good time for non-profits to market donation campaigns, around the time many people are celebrating positive life events, like holidays or graduations.”

The researchers note that hosting celebrations that increase perceived social support can be especially beneficial at places serving populations at greater risk of loneliness and isolation, like nursing homes or community centres.

They also note the importance of understanding the well-being benefits of celebrations for policymakers looking to implement regulations or measures that could impact social gatherings, like COVID lockdowns, to avoid negative consequences to mental health. They recommend that if organisers need to have virtual celebrations, they should involve some type of consumption and the marking of a separate, positive life event, so people leave the celebration feeling socially supported.

Source: Indiana University

Good Hydration may be Key to Healthy Ageing

Older woman smiling
Photo by Ravi Patel on Unsplasj

Adults who stay well-hydrated appear to be healthier, develop fewer chronic conditions, such as heart and lung disease, and live longer than those who may not get sufficient fluids, according to a study published in eBioMedicine.

Using health data gathered from 11 255 adults over a 30-year period, researchers analysed links between serum sodium levels (which increase with reduced fluid intake) and various indicators of health. They found that adults with serum sodium levels at the higher end of a normal range were more likely to develop chronic conditions and show signs of advanced biological aging than those with serum sodium levels in the medium ranges. Adults with higher levels were also more likely to die at a younger age.

“The results suggest that proper hydration may slow down aging and prolong a disease-free life,” said Natalia Dmitrieva, PhD, a study author and researcher at the National Heart, Lung, and Blood Institute (NHLBI).

The study expands on previous research from the scientists, which found links between high-normal serum sodium levels and increased risks for heart failure. Both findings came from the Atherosclerosis Risk in Communities (ARIC) study, which started in 1987.

For this latest analysis, researchers assessed information study participants shared during five medical visits – the first two when they were in their 50s, and the last between ages 70–90. Adults who had high levels of serum sodium at baseline check-ins or with underlying conditions, like obesity, that could affect serum sodium levels, were excluded.

The researchers then evaluated how serum sodium levels correlated with biological ageing, which was assessed through 15 health markers such as systolic blood pressure, cholesterol, and blood sugar. These provided insight about how well each person’s cardiovascular, respiratory, metabolic, renal, and immune system was functioning. They also adjusted for factors, like age, race, biological sex, smoking status, and hypertension.

They found that adults with higher levels of normal serum sodium, normallu between 135–146 milliequivalents per litre (mEq/L), were more likely to show signs of faster biological ageing. This was based on indictors like metabolic and cardiovascular health, lung function, and inflammation. For example, adults with serum sodium levels above 142mEq/L had a 10-15% associated increased odds of being biologically older than their chronological age compared to ranges between 137–142mEq/L, while levels above 144mEq/L correlated with a 50% increase. Likewise, levels of 144.5–146 mEq/L were associated with a 21% increased risk of premature death compared to ranges between 137–142mEq/L.

Similarly, adults with serum sodium levels above 142mEq/L had up to a 64% increased associated risk for developing chronic diseases like heart failure, stroke, atrial fibrillation and peripheral artery disease, as well as chronic lung disease, diabetes, and dementia. Conversely, adults with serum sodium levels between 138–140 mEq/L had the lowest risk of developing chronic disease.

The researchers caution that randomised, controlled trials are needed to prove an association between fluid intake and signs of ageing.

“People whose serum sodium is 142mEq/L or higher would benefit from evaluation of their fluid intake,” Dmitrieva said. She noted that most people can safely increase their fluid intake to meet recommended levels, which can be done with water as well as other fluids, like juices, or vegetables and fruits with a high water content. The National Academies of Medicine, for example, suggest that most women consume around 6-9 cups (1.5–2.2 litres) of fluids daily and for men, 8-12 cups (2–3 litres).

Others may need medical guidance due to underlying health conditions. “The goal is to ensure patients are taking in enough fluids, while assessing factors, like medications, that may lead to fluid loss,” said study author Manfred Boehm, MD, director of the Laboratory of Cardiovascular Regenerative Medicine at NHLBI. “Doctors may also need to defer to a patient’s current treatment plan, such as limiting fluid intake for heart failure.”

The authors also cited research that finds about half of people worldwide don’t meet recommendations for daily total water intake, which often starts at 6 cups (1.5 litres).

“On the global level, this can have a big impact,” Dmitrieva said. “Decreased body water content is the most common factor that increases serum sodium, which is why the results suggest that staying well hydrated may slow down the aging process and prevent or delay chronic disease.”

Source: NIH/National Heart, Lung and Blood Institute

Scientists Retract Controversial Omicron Origins Article

On December 1, Charité — Universitätsmedizin Berlin reported new findings on the origins of the SARS-CoV-2 variant Omicron, one of which was a “stepwise” emergence of the variant across Africa rather than the accepted scenario of it emerging in a single area around South Africa.

In light of new findings of contaminated samples used in the research, the team led by Prof Jan Felix Drexler has now retracted the article, which was published in the journal Science.

The new findings mean that some of the article’s statements are no longer provable beyond reasonable doubt, and the authors retracted their article in line with sound scientific procedure.

In the article entitled “Gradual emergence followed by exponential spread of the SARS-CoV-2 Omicron variant in Africa”, researchers came to the conclusion that the Omicron variant of SARS-CoV-2 emerged in western Africa a few months prior its eventual discovery in South Africa in early November. Shortly after the article was published, other scientists, such as SA’s Dr Tulio de Oliveira, called into question the plausibility of the genome sequences analysed in the study. Subsequent analysis of residual samples found evidence of contamination, the source of which can no longer be traced.

One of the article’s messages — that viruses with Omicron sequence signatures existed across the continent before Omicron was officially detected in South Africa — is based on collective data from PCR analysis done independently by laboratories in several African countries. However, the conclusive reconstruction of the virus’s evolution, another of the article’s key messages, is likely to be affected by sequence contamination not detected before analysis.

The contamination also makes it impossible to correct the analyses retrospectively in due time, because this would require additional analyses of thousands of patient samples from Africa that may not be available in sufficient quantity and quality. Therefore, in agreement with all the authors, the entire article is being retracted. The research group that ran the project is currently carrying out an evaluation and review of the analyses.

Prof Drexler and his team expressed regret for the incident and gratitude to their international colleagues for flagging the potential problems following the article’s publication.

Source: Charité – Universitätsmedizin Berlin